A biocompatible, photoresist derived, thin carbon substrate has been recently developed which promotes nerve proliferation and differentiation. A method which alters the substrate's physical and electrochemical properties by doping photoresist with magnetite nanoparticles has been developed to enhance the existing substrate's ability to foster cell growth. Rat pheochromocytoma cells were used for culture to test substrate-cell interactions. Varying the nanoparticle concentration on the surface produced increased surface roughness, electrical conductivity, cell concentration and average neurite length.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Rezhdo, Oljora
• Perrone, Matthew Scott

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042910-095329

Advisor

• Zhou, H Susan

Year

• 2010

Sponsor

• University of

Date created

• 2010-04-29

Resource type

• Major Qualifying Project

Major

• Chemical Engineering

Rights statement

• In Copyright

Last modified

• 2020-12-27