Student Work

Design of a Bioreactor for Tissue Engineered Vascular Grafts

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A vascular bioreactor is a device that simulates an in vivo environment to improve the structure and function of tissue engineered vascular grafts (TEVGs). TEVGs should be cultured in a dynamic environment that provides luminal laminar flow; this facilitates nourishment of the cells and prevents occlusion of the graft. In this study, we designed, manufactured, and validated a novel bioreactor system for TEVGs. The bioreactor design successfully provided luminal laminar flow, incorporated an isolated flow loop, prevented leakage, remained sterile, limited mounting time, accommodated different sized samples, was easy to machine and cost effective.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • E-project-042513-111922
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Year
  • 2013
Date created
  • 2013-04-25
Resource type
Major
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Last modified
  • 2021-02-02

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