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Measuring changes in bioavailability of artemisinin: in combination with flavonoids, phenolic acids, and monoterpene found in Artemisia annua

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Artemisinin, a potent antimalarial found in Artemisia annua, is currently used in combination with other antimalarial drugs (ACTs), mainly against Plasmodium parasites. Ingestion of A. annua dried leaves is more efficacious than ACT, possibly due to increased bioavailability of artemisinin. This project used a Caco-2 intestinal model to perform experiments showing the effects of specific phytochemicals on artemisinin transport. Artemisinin transport across Caco-2 monolayers varied with artemisinin concentration.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-042315-175751
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  • 2015
Date created
  • 2015-04-23
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