Student Work
Study of Protein Requirements for Histone Deposition
PublicDownloadable Content
open in viewerHistone deposition proteins CAF-1 and Asf-1 impact multiple aspects of chromosome formation and are essential in yeast to prevent DNA damage and avoid chromosomal rearrangement. Using fractionated yeast cell extracts, this MQP attempted to identify stimulatory factors which are necessary and sufficient for histone deposition by CAF-1 and/or Asf1. Identification of these cofactors, would provide insight into the reaction pathway and mechanism of histone deposition. Results were inconclusive, but improvements were proposed for the future success of this project.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Contributors
- Publisher
- Identifier
- E-project-042607-140705
- Advisor
- Year
- 2007
- Date created
- 2007-04-26
- Resource type
- Major
- Rights statement
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