Student Work

Synthesis of Near-IR Fluorophores Towards In Vivo Protein Detection

Public

Downloadable Content

open in viewer

Recent studies into oxazine derivative dyes have shown promising shifts in excitation and emission properties. For this MQP, the synthesis and spectral properties of two oxazine derivatives: 4-Ethyl-3,8,9,10-tetrahydro-2H-1,6,11-trioxa-8,13-diaza-4-azonia-pentacene; chloride (7) and 8-(3-Ethoxycarbonyl-propyl)-4-ethyl-3,8,9,10-tetrahydro-2H-1,6,11-trioxa-8,13-diaza-4-azonia-pentacene; chloride (8, 9) were studied. The electronic excitation and emission properties of compound 9 were examined in incremental pH solutions ranging from 1 to 11. In methanol maximum excitation of compound 9 was observed at 648.0 nm while maximum emission occurred at 674.26 nm. Consistency in the excitation and emission spectra show that compound 9 has strong pH stability.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Contributors
Publisher
Identifier
  • E-project-042910-162108
Advisor
Year
  • 2010
Sponsor
Date created
  • 2010-04-29
Resource type
Major
Rights statement

Relations

In Collection:

Items

Items

Permanent link to this page: https://digital.wpi.edu/show/5x21th03f