Student Work

Analysis of RNA Interference Pathways in C.elegans:Investigation of Argonaute Interactions in C. elegans using Yeast Two - Hybrid

Public

Downloadable Content

open in viewer

RNA interference (RNAi) is a sequence-specific silencing phenomenon that is conserved in animals, plants and some bacteria (Fire and Mello, 1998; Meister and Tuschl, 2004). At least 4 different AGO pathways are thought to function in the germline of C. elegans. In an effort to understand how these pathways remain independent from one another, we are using yeast two-hybrid to identify proteins that interact with and potentially regulate AGOs. The results showed colonies which grew on secondary selection plates indicated potential interacting proteins for the argonautes of interest.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Contributors
Publisher
Identifier
  • E-project-042513-112907
Advisor
Year
  • 2013
Sponsor
Date created
  • 2013-04-25
Resource type
Major
Rights statement
Last modified
  • 2023-09-19

Relations

In Collection:

Items

Items

Permanent link to this page: https://digital.wpi.edu/show/df65v925n