Several studies have shown that human mesenchymal stem cells (hMSCs) have the potential to be the futute of regenerative medicine based on their ability to rebuild diseased or damaged tissues. The difficulty involved with hMSCs is delivering these cells to the injured tissue site. Injection is the preferred method, but it has been shown that simple injection of hMSCs in media results in extreme turbulent flow, thus killing the cells. Hydrogels have been researched as a form of vehicle for hMSC transport. However, the delivery of the gel and cell viability remain a problem.  This project aims to seek the best overall hydrogel to act as the vehicle as well as a delivery mechanism that allows for simple, safe and convenient transport of hMSCs.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Mgbojikwe, Kene E.
• Shivaprakash, Jayanth Bhatta
• Bray, John Gerard
• Leung, Wai-Mun

Contributors

• Prescott, Al

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042408-114607

Advisor

• Gaudette, Glenn R.

Year

• 2008

Sponsor

• Crescent Innovations Inc.

Date created

• 2008-04-24

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright