Singlet oxygen can decompose toxic substances by oxidation, but its direct generation from atmospheric oxygen by a photosensitizer requires a light source. In this project, six derivatives of 2-pyridone that can reversibly trap singlet oxygen under irradiation and release it in the dark were studied. The rates of thermolysis of their endoperoxides were measured by UV-Vis spectroscopy. Theoretical modeling was also carried out with Gaussian 09. Overall, N-isoamyl-2-pyridone has the best release performance. This study also evaluates the effects of sterics and electronics on this trend, and discusses the possibility of theoretical modeling to evaluate N-substituted 2-pyridones. Pyridone samples investigated in this study were provided by Ventana Research Corporation.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Luo, Lan

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042611-141659

Advisor

• Connors, Robert E.

Year

• 2011

Date created

• 2011-04-26

Resource type

• Major Qualifying Project

Major

• Chemistry

Rights statement

• In Copyright