The intravenous administration of a lipid-based oxygen suspension has been shown to raise blood oxygen saturations to survivable levels in models of asphyxia. However, emergency situations often render intravenous access impossible, so the intraosseous (IO) route is sometimes used to obtain vascular access. This study examined the pharmacokinetics of infusion of a lipid-based oxygen suspension administered through an IO line. IO infusion raised the blood oxygen content of hypoxemic animals in a manner similar to IV infusion.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Reese, James Harold

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042811-144931

Advisor

• Adams, David S.

Year

• 2011

Date created

• 2011-04-28

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright