Student Work

Gold - Human Serum Albumin Contrast Agents

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Traditional contrast agents use inorganic compounds containing metal ions to differentiate tissue types in medical diagnostic imaging. These compounds suffer from toxicity and they do not target specific tissues. A human serum albumin and gold complex (Au@HSA) was synthesized via a biomineralization reaction to overcome these obstacles and the resulting compound was optically active, giving it potential as a contrast agent. Additionally, the Au@HSA was conjugated with the tumor targeting compound arginylglycylaspartic acid without losing its optical activity.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • E-project-042517-225308
Advisor
Year
  • 2017
Sponsor
Date created
  • 2017-04-25
Resource type
Major
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Last modified
  • 2020-11-19

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Permanent link to this page: https://digital.wpi.edu/show/rf55z9422