Using electrical impedance spectroscopy, three nanoparticle-based detection schemes were investigated. In particular, reproducibility and ease of amplification were thoroughly analyzed. Though all three configurations successfully detected the presence of the target molecule (human IgE), the sensor utilizing an aptamer sandwich mechanism generated reproducible, large impedance changes in the presence of human IgE.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Austin, John S.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-031610-014341

Advisor

• Zhou, H Susan

Year

• 2010

Date created

• 2010-03-16

Resource type

• Major Qualifying Project

Major

• Chemical Engineering
• Chemistry

Rights statement

• In Copyright

Last modified

• 2020-12-27