Faculty Advisor

Shannon, Thomas A.

Faculty Advisor

Shonat, Ross D.


The ethics associated with the engineering of animal models to study human diseases is developed and discussed. Experiments using engineered animals have led to cures and treatments for many diseases. The genotype, phenotype, history, treatments and animal models for various genetic diseases are discussed. An analysis is conducted on the benefits of animal research vs. the cost in pain that is endured by the engineered animals. The recommendations focus on reducing the number of animals used for experimentation on genetic diseases, stressing the possibility of research methods that do not require an animal model, and refining the process of experimentation to reduce the number of experiments and the pain caused to each animal.


Worcester Polytechnic Institute

Date Accepted

January 2002

Project Type

Interactive Qualifying Project


Restricted-WPI community only

Advisor Department

Humanities and Arts

Advisor Department

Biomedical Engineering