Title

Characterization of the Interaction Between Myosin XIa and RabA4 in Physcomitrella patens

Faculty Advisor

Vidali, Luis

Abstract

In the moss Physcomitrella patens, myosin XI mediated polarized tip growth is essential for growth and expansion. It has been hypothesized that, during polarized growth, secretory vesicles move to the tip of the expanding cell via an interaction between the myosin XI globular tail and RabA4. In this study, we show that several mutations in the putative binding region for RabA4 on the myosin XI tail produce the same phenotype as a myosin XIa knockdown, suggesting an interaction with RabA4.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2012

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

Advisor Program

Biology and Biotechnology

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