In this project, an experiment was conducted in order to examine the effects of vimentin on cellular dynamics. The response and relaxation process of normal fibroblast cells and vimentin knockdown cells were tested and compared. The result shows that the vimentin-knockdown fibroblasts are much easier to change orientation than the normal fibroblasts. However, the contamination problem could affect the accuracy of the experiment, and it is advised for future researchers to refine the protocol in order to eliminate contamination which might lead to more accurate results.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Jing, Yu

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-050218-170333

Advisor

• Wen, Qi

Year

• 2018

Date created

• 2018-05-02

Resource type

• Major Qualifying Project

Major

• Physics

Rights statement

• In Copyright