Faculty Advisor

Servatius, Brigitte

Abstract

In this project, we studied transcriptional regulation in C. elegans through a network approach. We used techniques analyzing degree distribution, motifs, gene regulation subgraphs etc. to investigate various properties of the network. Our motif analysis discovered previously unknown motifs that are likely to have biological significance. We introduced a new technique for quantifying amount of gene regulation and formulated a new hypothesis to predict autoregulation. Our results will serve as a basis for future biological experiments.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2010

Major

Computer Science

Major

Mathematical Sciences

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Mathematical Sciences

Share

COinS