Faculty Advisor

Pins, George

Abstract

Infected wounds are one of the most prominent health problems today, and many different methods of treatment exist. However, these treatments have their limitations and are often costly. By combining organic essential oils with a pre-existing silver antimicrobial, we can provide a more effective, less expensive wound dressing for treatment of infected wounds. After a series in vitro and in vivo tests for antimicrobial efficacy, these experiments validate the combination of actives which inhibit and kill specific wound pathogens in a hydrocolloid wound dressing. We used these results to design a three-layered, two-component dressing, to diffuse antimicrobials and to inhibit growth of bacteria as well as to remain mechanically stable in a wound environment.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2006

Major

Biomedical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biomedical Engineering

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