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SLiM Analysis in Human SALMs and Linx

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Leucine rich repeat and Immunoglobulin domain (LIG) containing proteins play a critical role in protein-protein and intercellular interactions. While the extracellular domains of many of these proteins have been studied in depth, little is known about their intracellular domains, which can add to our knowledge of LIG protein functionality. Here, within the intracellular domains of two subfamilies of LIG molecules, the SALM and Linx subfamilies, sequences that are conserved over evolutionary time in four species: human, mouse, chicken, and elephant shark, have been identified and represent putative functionally relevant Short Linear Motifs, SLiMs.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-012617-154336
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  • 2017
Date created
  • 2017-01-26
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Permanent link to this page: https://digital.wpi.edu/show/v979v4270