Lyme disease is caused by Borrelia burgdorferi, a spirochete that infects across phyla from ticks to humans. BadR and Hbb are transcriptional repressors that are involved in transitioning the spirochete for survival in mammals, however their targets are largely unknown. We created a reporter system to screen candidate promoters for regulation by BadR and
Worcester Polytechnic Institute
Biology and Biotechnology
Major Qualifying Project
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