MIG-10 is a protein known to be involved in axon guidance and neuronal migration in early development in C. elegans. In an effort to better understand the protein's function, this project used the yeast two hybrid system to screen a cDNA library (representing the entire C. elegans genome) for proteins with which MIG-10 interacts. The idea is if we can associate it with proteins of known function, we'll have a better idea as to what MIG-10 itself does. Our research revealed that MIG-10 interacts with (among other proteins) ABI-1, which is a component of actin polymerization machinery.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Gosselin, Jennifer Marie
• O'Toole, Sean Michael

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042308-192844

Advisor

• Ryder, Elizabeth F.

Year

• 2008

Date created

• 2008-04-23

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright

Last modified

• 2021-02-02