Faculty Advisor

Zhou, Hong Susan

Abstract

A biocompatible, photoresist derived, thin carbon substrate has been recently developed which promotes nerve proliferation and differentiation. A method which alters the substrate's physical and electrochemical properties by doping photoresist with magnetite nanoparticles has been developed to enhance the existing substrate's ability to foster cell growth. Rat pheochromocytoma cells were used for culture to test substrate-cell interactions. Varying the nanoparticle concentration on the surface produced increased surface roughness, electrical conductivity, cell concentration and average neurite length.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2010

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemical Engineering

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