Parasitic nematodes may cause biomedical and agricultural problems by avoiding host immune systems through changes in surface composition during infection, a process we call surface antigen switching. C. elegans is a free-living nematode serving as a model organism for antigen switching. srf-6 mutations change the developmental surface antigen display, and previous evidence suggests that srf-6 may be identical to the MAPKKK gene nsy-1. Complementation tests between srf-6 and nsy-1 mutants were conducted to support the hypothesis that srf-6 and nsy-1 affect the same genetic function.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Isenhart, Randi Leigh

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042815-210102

Advisor

• Politz, Samuel M.

Year

• 2015

Date created

• 2015-04-28

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright