Faculty Advisor

Dominko, Tanja

Faculty Advisor

Rolle, Marsha W.

Abstract

Periodontitis, if left untreated, leads to gum recession, tooth decay and eventual tooth loss. The current treatment to regenerate gingival tissue is to use a graft. Graft materials either require surgical harvesting or tear easily. The goal of this project was to evaluate a synthetic scaffold as a scaffold material to mimic properties of gum tissue. The results qualitatively showed an increase in cell number and minimal collagen deposition on the scaffold. The scaffold material was mechanically stronger than the benchmark commercially available acellular graft. We concluded that the synthetic scaffold has the potential to be a material used in gingival tissue repair but it presents many limitations that would have to be addressed and further testing would be required.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2013

Major

Biology and Biotechnology

Major

Biomedical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

Advisor Department

Biomedical Engineering

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