Faculty Advisor

Zhou, Hong Susan

Abstract

Photoresist derived carbon films offer a unique set of properties that may prove useful as substratum for neuron cell growth. At this early stage in realizing the material's potential as a platform for neuron culture, it is necessary to examine surface properties and neuronal cell behavior. Surfaces are characterized by means relevant for studying cell-surface response, including electrochemistry and surface energy. Comparing gene expression levels, adhesion and morphology of PC12 cells grown on photoresist derived carbon to that of alternative materials elucidates cell-surface interactions in context of known surface characteristics. Results show that photoresist derived carbon is a viable alternative to current materials, offering the advantages of modification and electrical properties.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2009

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemical Engineering

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