Zhou, Hong Susan
Photoresist derived carbon films offer a unique set of properties that may prove useful as substratum for neuron cell growth. At this early stage in realizing the material's potential as a platform for neuron culture, it is necessary to examine surface properties and neuronal cell behavior. Surfaces are characterized by means relevant for studying cell-surface response, including electrochemistry and surface energy. Comparing gene expression levels, adhesion and morphology of PC12 cells grown on photoresist derived carbon to that of alternative materials elucidates cell-surface interactions in context of known surface characteristics. Results show that photoresist derived carbon is a viable alternative to current materials, offering the advantages of modification and electrical properties.
Worcester Polytechnic Institute
Major Qualifying Project
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