Faculty Advisor

MacDonald, John C.

Abstract

Porous metallic-organic frameworks (MOFs) consisting of crystalline coordination polymers are of interest as materials for heterogeneous catalysis. We currently are exploring the activity of copper-containing MOFs (Cu-MOFs) for catalyzing Huisgen 1,3-dipolar cycloaddition (“Click”) reactions between substituted alkynes and azides. Our goals were to determine if Cu-MOFs show catalytic activity, and whether the sorbent properties and high density of metal ions present in Cu-MOFs lead to more efficient catalysis of Click reactions compared to homogeneous catalysts. Toward that goal, this research has focused in two areas: (1) synthesis of substituted triazoles via the “Click” reaction using the Cu-MOF Cu(im)2 as the catalyst; and (2) investigation of the reaction rates for those reactions.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2012

Major

Chemistry

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemistry and Biochemistry

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