Student Work
Protein Dynamics: Probing biological processes at the molecular level
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open in viewerProteins are essential for all cellular processes. Hemoglobin is one of the most well studied proteins and is the standard model for allosteric regulation. Allostery is an important, yet poorly understood, component of biochemistry. Using Normal Mode Analysis (NMA), the dynamics of scapharca dimeric hemoglobin, an allosteric protein,have been simulated and correlate with previous crystallographic data. This indicates that NMA may be a useful tool for predicting early intermediate structures and explaining allosteric regulation at the molecular level.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Contributors
- Publisher
- Identifier
- E-project-031407-165815
- Advisor
- Year
- 2007
- Sponsor
- Date created
- 2007-03-14
- Resource type
- Major
- Rights statement
- Last modified
- 2023-09-20
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