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Characterization of Cancer Stem Cells in Tumor Pathogenesis

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Recent studies have shown that many cancerous tumors contain "cancer stem cells" (CSCs) that may be responsible for the self-renewing properties of the tumor. A common cancer treatment, chemotherapy, targets rapidly dividing cells, but could possibly be ignoring the more slowly dividing CSCs. The CSCs were characterized in a variety of tumors using immunofluorescence to identify stem cell markers after treatment with a common chemotherapy, Doxorubicin. The resulting data show statistically significant evidence for the presence of stem cell markers in cells left behind after chemotherapy treatment.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-043009-134220
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  • 2009
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  • 2009-04-30
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