Faculty Advisor

Adams, David S.

Abstract

Recent studies have shown that many cancerous tumors contain "cancer stem cells" (CSCs) that may be responsible for the self-renewing properties of the tumor. A common cancer treatment, chemotherapy, targets rapidly dividing cells, but could possibly be ignoring the more slowly dividing CSCs. The CSCs were characterized in a variety of tumors using immunofluorescence to identify stem cell markers after treatment with a common chemotherapy, Doxorubicin. The resulting data show statistically significant evidence for the presence of stem cell markers in cells left behind after chemotherapy treatment.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2009

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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