Faculty Advisor
Adams, David S.
Sponsor
UMass Medical School
Abstract
Recent studies have shown that many cancerous tumors contain "cancer stem cells" (CSCs) that may be responsible for the self-renewing properties of the tumor. A common cancer treatment, chemotherapy, targets rapidly dividing cells, but could possibly be ignoring the more slowly dividing CSCs. The CSCs were characterized in a variety of tumors using immunofluorescence to identify stem cell markers after treatment with a common chemotherapy, Doxorubicin. The resulting data show statistically significant evidence for the presence of stem cell markers in cells left behind after chemotherapy treatment.
Publisher
Worcester Polytechnic Institute
Date Accepted
April 2009
Major
Biology and Biotechnology
Project Type
Major Qualifying Project
Copyright Statement
All authors have granted to WPI a nonexclusive royalty-free license to distribute copies of the work, subject to other agreements. Copyright is held by the author or authors, with all rights reserved, unless otherwise noted.
Accessibility
Unrestricted
Advisor Department
Biology and Biotechnology
Advisor Program
Biology and Biotechnology