Faculty Advisor

Politz, Samuel M

Abstract

A class of Caenorhabditis elegans genes encodes amino acid sequence motifs similar to surface proteins of the parasitic nematode, T. canis, and therefore can serve as a model for the parasite's nematomucin expression. Putative surface protein expression in C. elegans surface mutants was compared to wild-type expression using anti-peptide antibodies. SDS-PAGE determined protein viability and western blotting revealed protein expression similarities. bah-1(br1), srf-2(br3), bus-4(br4), bah-2(br7), and srf-6(yj13) showed a 52 kDa protein band similar to the wild-type, and bah-1(br1) expressed an additional 36 kDa protein.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2008

Major

Biochemistry

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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