Faculty Advisor

Gaudette, Glenn R

Abstract

Several studies have shown that human mesenchymal stem cells (hMSCs)have the potential to be the futute of regenerative medicine based on their ability to rebuild diseased or damaged tissues. The difficulty involved with hMSCs is delivering these cells to the injured tissue site. Injection is the preferred method, but it has been shown that simple injection of hMSCs in media results in extreme turbulent flow, thus killing the cells. Hydrogels have been researched as a form of vehicle for hMSC transport. However, the delivery of the gel and cell viability remain a problem. This project aims to seek the best overall hydrogel to act as the vehicle as well as a delivery mechanism that allows for simple, safe and convenient transport of hMSCs.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2008

Major

Biomedical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biomedical Engineering

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