Faculty Advisor

Connors, Robert E.

Abstract

Singlet oxygen can decompose toxic substances by oxidation, but its direct generation from atmospheric oxygen by a photosensitizer requires a light source. In this project, six derivatives of 2-pyridone that can reversibly trap singlet oxygen under irradiation and release it in the dark were studied. The rates of thermolysis of their endoperoxides were measured by UV-Vis spectroscopy. Theoretical modeling was also carried out with Gaussian 09. Overall, N-isoamyl-2-pyridone has the best release performance. This study also evaluates the effects of sterics and electronics on this trend, and discusses the possibility of theoretical modeling to evaluate N-substituted 2-pyridones. Pyridone samples investigated in this study were provided by Ventana Research Corporation.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2011

Major

Chemistry

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemistry and Biochemistry

Advisor Program

Chemistry and Biochemistry

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