Dittami, James P.
The "photoinitiated intramolecular ylide-alkene cycloaddition reaction" which was developed in our laboratory provides a method for construction of up to three rings and six chiral centers in a single experimental operation from relatively simple starting materials. This project has attempted to utilize this reaction to quickly synthesize novel materials which incorporate catechol bioisosteres into the organic scaffold in the hopes of imparting potentially useful bio-activity to the new molecules.
Worcester Polytechnic Institute
Major Qualifying Project
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Chemistry and Biochemistry