Faculty Advisor
Ryder, Elizabeth F.
Abstract
The C. elegans protein MIG-10 is a cytoplasmic signaling protein known to facilitate neuronal migrations during development of the worm. LIN-53 is a nucleosome remodeling factor associated with transcriptional repression in C. elegans. Biochemical analyses were performed using co-immunoprecipitation and western blotting techniques to assess the interaction of these two proteins. Preliminary results suggest a potential interaction between LIN-53 and MIG-10. Work is in progress to determine whether lin-53 mutations affect neuronal migrations in C. elegans.
Publisher
Worcester Polytechnic Institute
Date Accepted
June 2012
Major
Biology and Biotechnology
Project Type
Major Qualifying Project
Copyright Statement
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Accessibility
Unrestricted
Advisor Department
Biology and Biotechnology