Faculty Advisor

Buckholt, Michael Allan

Faculty Advisor

Shell, Scarlet

Abstract

Antibiotic resistance has increased for many different diseases including tuberculosis. Scientists have begun to seek ways and places to discover new antibiotics to combat this resistance. Studies over the last 60 years suggest that pathogen-inhibiting bacteria can be found in soil. A number of bacterial isolates potentially producing antibiotic compounds have been found in the soil by students in the Microbes to Molecules laboratory course at Worcester Polytechnic Institute (WPI). This project tested those isolates for the ability to inhibit the growth of Mycobacterium smegmatis, a model bacteria for Mycobacterium tuberculosis. The goal of the project described here was to identify isolates capable of inhibiting M. smegmatis and determine the mechanism(s) of inhibition.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2017

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

Advisor Program

Biology and Biotechnology

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