Antiproliferative effects of the compound, artemisinin, have been observed in several breast cancer lines. Whole plants extracts appear to be more efficacious than the pure compound in the treatment of diseases such as malaria. In our studies, MCF-7 breast cancer cells were treated with purified artemisinin and extracts of the whole plant Artemisia annua to compare the effects. These results suggest that extracted artemisinin extract contains compounds with antagonistic effects which may inhibit its effects in cancer therapy.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Rogers, Jake Francis
• Seymour, Rebecca Lyn

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042816-134549

Advisor

• Buckholt, Michael Allan
• Rulfs, Jill

Year

• 2016

Date created

• 2016-04-28

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright