Faculty Advisor

Adams, David S.

Abstract

The goal of this MQP was to identify and characterize differentially expressed genes associated with Listeria monocytogenes infection in two strains of mice, BALB/cbyj (Listeria sensitive) and C57BL/6ByJ (Listeria resistant). We identified several genes both upregulated and deregulated by the host during infection, and mapped one gene's chromosomal location (though inconclusively) to gain a more complete understanding of the biochemical processes involved in the innate immune response.

Publisher

Worcester Polytechnic Institute

Date Accepted

December 2004

Major

Technical, Scientific and Professional Communication

Major

Biochemistry

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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