Faculty Advisor

Buckholt, Michael Allan

Faculty Advisor

Farny, Natalie

Abstract

Arsenic contamination of water supplies is a global concern. Stress granules (SGs) are cytoplasmic aggregations of RNA and protein formed in response to myriad environmental stresses, including arsenic. Acute and sub-lethal chronic levels of arsenic were tested for effects on SG formation. High level acute arsenic exposure resulted in maximal SG formation while low acute exposure had comparable results to sub-lethal chronic exposure. The results suggest that even trace amounts of heavy metals, when exposed chronically, cause considerable cellular stress.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2015

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

Advisor Department

BIO

Advisor Program

Biology and Biotechnology

Advisor Program

BIO

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