Faculty Advisor

Buckholt, Michael Allan

Faculty Advisor

Rulfs, Jill

Abstract

Artemisinin, an antimalarial treatment derived from Artemisia annua, reacts with ferrous compounds, generating free radicals unless hindered by antioxidants. High iron levels and low antioxidant levels of cancer cells make artemisinin a potentially effective treatment. We utilized MTT assays to assess artemisinin’s effect on MCF7 breast cancer cells. Artemisinin upregulated cell proliferation and appeared to affect the cells’ morphology, which could impact tumor development.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2017

Major

Biology and Biotechnology

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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