The heart does not regenerate new tissue when myocardium dies following acute myocardial infarction. We have undertaken an iterative process to design and test a patch that will replace infarcted tissue and induce myocardial regeneration to improve heart function. The result is a composite scaffold design composed of an endocardial patch to provide mechanical stability and an injectable filler material to provide a regenerative scaffold environment. This project provides a vital first step toward a final solution for myocardial regeneration.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Filipe, Daniel V.
• Singh, Deep Arjun
• McBride, Nicholas S.
• Proulx, Megan K.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-033007-121423

Advisor

• Pins, George D
• Gaudette, Glenn R.

Year

• 2007

Date created

• 2007-03-30

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright

Last modified

• 2021-02-01