University of Massachusetts Medical Center
The hepatitis C virus infects more than 170 million people worldwide. Many of the HCV deaths have been a result of drug resistance. It is essential for researchers to continue to modify the molecules to create a greater variety of drug analogues, and in doing so create one that is the solution to the HCV epidemic. HCV drug analogs that lack a side chain are less hindered and more adaptable in fighting the mutant virus; drugs of this molecular form should be focused on to produce an optimal drug response to the virus.
Worcester Polytechnic Institute
Major Qualifying Project
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Chemistry and Biochemistry
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