Faculty Advisor

Heilman, Destin

Center

University of Massachusetts Medical Center

Abstract

The hepatitis C virus infects more than 170 million people worldwide. Many of the HCV deaths have been a result of drug resistance. It is essential for researchers to continue to modify the molecules to create a greater variety of drug analogues, and in doing so create one that is the solution to the HCV epidemic. HCV drug analogs that lack a side chain are less hindered and more adaptable in fighting the mutant virus; drugs of this molecular form should be focused on to produce an optimal drug response to the virus.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2012

Major

Chemistry

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemistry and Biochemistry

Project Center

University of Massachusetts Medical Center

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