Faculty Advisor

Adams, David S.

Abstract

The heterotetrameric hemoglobin (HbII) from the blood clam Scapharca inequivalvis assembles from two heterodimers and provides a simple system to analyze the allosteric mechanisms in which unlike subunits bind ligands cooperatively. By finding a more effective way to produce HbII in lab, as well as HbI, the homodimeric hemoglobin from the same organism, work can continue forward on the allosteric and kinetic studies of this interesting protein.

Publisher

Worcester Polytechnic Institute

Date Accepted

January 2008

Major

Biochemistry

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biology and Biotechnology

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