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The Role of AIM2 in Inflammatory Gene Expression

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The importance of the cytosolic receptor, absent in melanoma 2 (AIM2), has recently been discovered. Its influence on inflammatory gene expression is essential for proper inflammatory response. In this study, inflammatory gene expression in wild type macrophages was observed, revealing a key role of AIM2 in certain inflammasome gene expressions. With a combination of the data gathered and additional experimentation, the role of AIM2 in inflammatory gene expression can be appreciated.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-030311-103747
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Year
  • 2011
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Date created
  • 2011-03-03
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