The MIG-10 protein has been shown to be involved in cell migration and axon guidance in C. elegans; however, the exact mechanism is still unknown. Previous studies suggest several proteins may interact with MIG-10, including ABI-1, LIN-53, and UNC-53. To further investigate the function of these proteins, viable mutant strains were created and effects on cell migration and process guidance were assessed in vivo. Results suggest that ABI-1, a component of the actin polymerization machinery, and LIN-53, a nucleosome remodeling factor, both have an effect on neuronal cell migration.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Sullivan-Keizer, Jessica

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-060209-121908

Advisor

• Ryder, Elizabeth F.

Year

• 2009

Date created

• 2009-06-02

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright

Last modified

• 2021-02-02