Nemucore Medical Inovations
The most daunting obstacle in the treatment of Glioblastoma Multiforme (GBM) lies with the impenetrability of the Blood Brain Barrier. This project aimed to design and engineer nanomedicines that have the aptitude to overcome this complication. The method of manufacturing the nanomedicines allowed for a variety of chemotherapeutics to be encapsulated. Once the nanomedicines were proven to be stable, cytotoxicity assays were conducted. GBM specific drugs were not as effective as broad-spectrum chemotherapeutics, even when combined with known pro-apoptotic factors.
Worcester Polytechnic Institute
Major Qualifying Project
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Chemistry and Biochemistry