Faculty Advisor

Roberts, Susan Celia

Abstract

The National Cancer Institute previously performed a high throughput screening to identify over 88,000 extracts with anticancer properties. This project aims to improve upon this screening system and develop a high-throughput screening system with the use of plant cell extracts to produce more reliable and consistent results, which can potentially lead to the discovery of novel specialized metabolites. By optimizing the solvent concentration and verifying the effects of known paclitaxel compounds, we were able to assess the effects of the Taxus cultures to further verify the effectiveness of our screening platform.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2018

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemical Engineering

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