Dittami, James P.
A computational method known as the Similarity Ensemble Approach (SEA) was used to predict drug-target interactions for molecular scaffolds previously made in the Dittami lab. Through three different analyses of this SEA data, the most promising scaffolds were determined. These scaffolds will then be synthesized and the predictions will be validated through a biological assay.
Worcester Polytechnic Institute
Major Qualifying Project
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Chemistry and Biochemistry