The project goal was to design a device to study the effects of directional stretch on model wound tissue in vitro to better understand cell-mediated matrix remodeling. Strip biaxial strain was attempted by varying the geometry of loading post platens of a commercial vacuum-driven cell-stretching device. FEA produced theoretical strain distributions and deformation software was used to validate the actual strain dispersal. Results from two novel platen designs can be used to improve production of accurate scar formation in vitro.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Cutuli, Kate E.
• Holmes, Megan Elizabeth
• Kahan, Marissa C.
• Dufour, Danielle M.

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042805-154003

Advisor

• Billiar, Kristen

Year

• 2005

Date created

• 2005-04-28

Location

• Worcester

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright