Student Work

T6α EFFECTOR FUNCTIONS AND MEMORY RESPONSE

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The purpose of this project was to analyze the function of a newly discovered subtype of CD8+ cell in mice, the T6-alpha subtype. Through assays of in vitro stimulation, cytotoxicity, and secondary memory responses in vivo, we explored the function of the T6-alpha subset of CD8+ T- cells. The data show that in response to an influenza virus infection in mice, the T6-alpha cells produce large quantities of IFN-gamma, lesser amounts of IL-2, and no detectable TNF- alpha and IL17. Future experiments focusing on T6- alpha kinetics and in vivo function could aid in development of future immune treatments.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-030712-135621
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  • 2012
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Date created
  • 2012-03-07
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