Clark, William M.
Kmiotek, Stephen J.
The purpose of this project was to investigate the use of thermally differentiated water steams (TDWS) to determine mixing dynamics in Sunovion Pharmaceuticals’ Buchi CR-60 reactor. The team used two methods: decolorization with phenolphthalein, and positive colorization with methylene blue dye. Decolorization allowed the team to find slow mixing zones to determine probe placement for TDWS. Positive colorization confirmed mixing times through modeling the vessel with DynoChem software. The team experimented with TDWS, with attention to probe placement and the ratios between bulk and addition phases. The team presented its findings emphasizing the variables which affect the tested methods so Sunovion can use an approach which resembles their real world application.
Worcester Polytechnic Institute
Humanities and Arts
Major Qualifying Project
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