There exists a need for inexpensive and efficient methods to isolate single cells, especially single tumor cells for single cell analysis to improve treatment methods. We developed a microfluidic device that traps single beads ranging from 38 to 45 µm, similar to mammalian cells. Our results suggest our device could trap single beads in 60 µm microwells, indicating this device could allow isolation of similarly-sized cells. Our device could be used for pharmacological testing for personalized medicine and other applications.
Worcester Polytechnic Institute
Major Qualifying Project
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