Faculty Advisor

Camesano, Terri Anne

Abstract

Biofilms are communities of bacteria that grow on surfaces and are encased in an extracellular matrix and are problematic due to their resistance to antibiotics. Cranberries have been found to have associated health benefits such as prevention of recurrent UTIs. Cranberry juice contains anthocyanidins, flavanol glycosides, phenolic acids and proanthocyanidins (PACs). Previous studies have presented evidence that the A-linked PACs found in the American cranberry have an impact on biofilms, however very few studies have evaluated the effects of only anthocyanidins. We used a 96 well assay to compare the effects of PACs, anthocyanidins, and crude extracts on S. aureus and E. coli. Our results confirm that PACs and crude have an effect on biofilm development, and anthocyanidins show promise.

Publisher

Worcester Polytechnic Institute

Date Accepted

April 2013

Major

Chemical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Chemical Engineering

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