Faculty Advisor

Gaudette, Glenn R

Faculty Advisor

Ryder, Elizabeth F

Abstract

This project developed a scalable method to produce cardio-myocytes from human mesenchymal stem cells (hMSCs) for use as a therapy for myocardial infarctions. Embryoid bodies (EBs) formed from hMSCs produced cardiac cells. To increase the production of EBs, a non-adhesive well structure was developed and tested. To increase the percentage of cardiac cells resulting from the process, platelet derived growth factor was used as a supplement. These novel methods will ease the process and increase the yield of cardiac cells.

Publisher

Worcester Polytechnic Institute

Date Accepted

May 2007

Major

Biology and Biotechnology

Major

Biomedical Engineering

Project Type

Major Qualifying Project

Accessibility

Unrestricted

Advisor Department

Biomedical Engineering

Advisor Department

Biology and Biotechnology

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